Course review

B2.2 Organelles and compartmentalization

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Learning objective

B2.2.1—Organelles as discrete subunits

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• Organelles are discrete cell subunits adapted for specific functions • Nuclei, chloroplasts, mitochondria, vesicles, ribosomes, and plasma membrane are organelles • Cell wall, cytoskeleton, and cytoplasm are not usually considered organelles

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B2.2.2—Nucleus-cytoplasm separation

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• The nuclear envelope protects DNA and separates transcription from translation • Introns can be removed from pre-mRNA by RNA splicing before translation • Nuclear pores regulate mRNA export and protein import using selective transport

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B2.2.3—Advantages of compartmentalization

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• Compartmentalization concentrates enzymes, substrates, and suitable pH for specific reactions • It separates incompatible biochemical processes so they can be controlled • Lysosomes and phagolysosomes contain acidic hydrolytic digestion away from cytoplasm

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