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6.10—B cells and T cells

Syllabus
2021
Objective
6.10
Level
A2

T cells clone and differentiate to coordinate or kill

A T cell with the matching receptor binds antigen presented on a cell surface, then divides by mitosis to make clones. The clones differentiate into helper, killer and memory T cells.

Helper T cells release signals that activate B cells; killer T cells destroy infected cells displaying the relevant antigen; memory T cells make a later response faster.

An infected body cell can present a viral antigen and activate a matching killer T cell. A helper T cell does not itself secrete the pathogen-specific antibody; it supports the B-cell response.

T-cell receptor specificity is not the same as antibody secretion. State the antigen-presenting cell and the T-cell subtype before describing the outcome.

ConceptA-Level Edexcel Biology A2