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IB Biology SLD1.3 Mutation and gene editingQuestion Bank

Question 7

[Maximum number: 1]

A mutation in which type of cell could be inherited?

A

Beta cell in the pancreas

B

T-cell in the lymph

C

Sperm cell in the testis

D

Skeletal muscle cell in the diaphragm

Question 2

[Maximum number: 2]

Psammonobiotus balticus belongs to a group of protists (unicellular eukaryotic organisms) that have a shell surrounding most of the cell, which provides shelter from predators. The graph shows the frequency of varying shell lengths in a population of P. balticus.

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Question 2(c)

(a)

Mutations may increase variation within a species. Compare and contrast substitution and insertion mutations.

[ 2 ]

Question 8

[Maximum number: 1]

What is a feature of mutations?

A

They occur randomly.

B

They only occur in germ cells.

C

The frequency cannot be increased by external factors.

D

They only occur in certain base sequences of the genome.

Question 12

[Maximum number: 1]

What is a gene mutation?

A

Failure of chromosome pairs to separate properly during cell division

B

Changes to genes caused by natural selection

C

Changes to the nucleotide sequence of the genetic material

D

Changes in karyotypes

Question 12

[Maximum number: 1]

How is a new allele produced?

A

Cloning

B

Mutation

C

Differentiation

D

Natural selection

Question 13

[Maximum number: 1]

What occurs during gene mutation?

A

Allele change

B

Crossing over

C

Non-disjunction

D

Evolution

Question 13

[Maximum number: 1]

One type of gene mutation involves a base substitution.

Table

What are the consequences of the base substitutions in the two new sequences of DNA?

A

Both are mutations that would result in different polypeptides.

B

Sequence 2 would result in a changed polypeptide but sequence 1 would not.

C

All three DNA sequences would translate into the same polypeptide.

D

Only the original DNA and sequence 2 would translate into the same polypeptide.

Question 13

[Maximum number: 1]

Which of the following is the cause of sickle-cell anemia?

A

Tryptophan is replaced by leucine.

B

Leucine is replaced by valine.

C

Glutamic acid is replaced by valine.

D

Lysine is replaced by glutamic acid.

Question 13

[Maximum number: 1]

In some people, hemoglobin always contains the amino acid valine in place of a glutamic acid at one position in the protein. What is the cause of this?

A

An error in transcription of the hemoglobin gene

B

An error in translation of the mRNA

C

Lack of glutamic acid in the diet

D

A base substitution in the hemoglobin gene

Question 15

[Maximum number: 1]

The Cancer Council of New South Wales has stated that one in five cancer deaths are caused by smoking. How can smoking cause cancer?

A

20 % of smokers get cancer.

B

Cigarette smoke contains mutagenic chemicals.

C

Smoking reduces the rate of mitosis in cells.

D

Smoking is addictive.

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