• Homeostasis maintains a stable internal environment within narrow limits
• Variables include body temperature, blood pH, glucose, gases, ions, and osmotic concentration
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Start with the concept explanation, then practise to create mastery evidence.
2
Learning objective
D3.3.2—Negative feedback loops
New
• Negative feedback detects deviation from a set point and reverses it
• Receptors, coordinators, effectors, and feedback loops restore normal conditions
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Mastery
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Start with the concept explanation, then practise to create mastery evidence.
3
Learning objective
D3.3.3—Blood glucose regulation
New
• Beta cells secrete insulin when blood glucose rises
• Alpha cells secrete glucagon when blood glucose falls, affecting liver and muscle stores
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Mastery
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.
4
Learning objective
D3.3.4—Diabetes
New
• Type 1 diabetes results from autoimmune destruction of pancreatic beta cells
• Type 2 diabetes involves insulin-receptor/response failure and is linked to lifestyle risk factors
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Mastery
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.
5
Learning objective
D3.3.5—Thermoregulation
New
• Thermoregulation uses negative feedback to maintain core temperature near 37 °C
• Thermoreceptors signal the hypothalamus, which coordinates skin, muscles, liver, and hormones
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Mastery
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.
6
Learning objective
D3.3.6—Thermoregulation mechanisms
New
• Cooling uses vasodilation, sweating, and hairs lying flat
• Warming uses vasoconstriction, reduced sweating, shivering, metabolic heat, and brown fat
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Mastery
0
Attempts
0
Mistakes
Start with the concept explanation, then practise to create mastery evidence.