1.3 The Neuron and Neural Firing
- Syllabus
- 2025
- Topic
- 1.3
- Level
- —
Neurons transmit information; glial cells make that transmission possible by providing structure, insulation, communication support, and waste transport. Together they form the working cellular basis of behavior and mental processes: neurons carry messages, while glia maintain the conditions in which neural networks can function.
| Cell type | Main learning job |
|---|---|
| Neuron | Transmits information through the nervous system |
| Glial cell | Supports neural structure, insulation, communication, and waste transport |
A spinal reflex shows CNS and PNS neurons working as one pathway: (1) a sensory neuron carries information from a stimulus toward the spinal cord; (2) an interneuron in the spinal cord connects and processes the signal; (3) a motor neuron carries the response command toward the body. Because the spinal cord coordinates this pathway, a response can begin without waiting for deliberate conscious processing.
Do not treat glia as message-carrying neurons or the reflex as a single-neuron event. The learning point is coordinated function among sensory neurons, interneurons, motor neurons, and supporting glial cells.
Neural transmission follows an ordered cycle. A neuron begins at resting potential. If incoming stimulation reaches threshold, depolarization produces an action potential according to the all-or-none principle: the neuron fires fully rather than partially. A refractory period follows before the neuron can fire normally again. At the next cell, chemical messengers influence whether another action potential becomes more or less likely; reuptake removes released neurotransmitter back into the sending cell.
| Signal idea | Effect or distinction |
|---|---|
| Excitatory message | Makes an action potential more likely |
| Inhibitory message | Makes an action potential less likely |
| Neurotransmitter | Communicates within the nervous system; its function can depend on location |
| Hormone | Acts outside the nervous system in ways that can resemble neurotransmitter signaling |
AP Psychology limits neurotransmitters here to dopamine, serotonin, norepinephrine, glutamate, GABA, endorphins, substance P, and acetylcholine. The listed hormones are adrenaline, leptin, ghrelin, melatonin, and oxytocin. A disruption anywhere in transmission can change behavior or mental processes; multiple sclerosis and myasthenia gravis are examples linked to disrupted signaling.
Exam boundary: the sodium–potassium pump is outside scope. Detailed endocrine-gland information is also excluded here, except for the pituitary gland where Topic 1.4 explicitly includes it.
Psychoactive drugs change behavior and mental processes by altering neural communication. Their effects depend on where they intervene: they may encourage receptor activity, block it, or keep a neurotransmitter available for longer. A drug’s neural mechanism therefore leads to psychological and physiological consequences.
| Mechanism | Effect on communication |
|---|---|
| Agonist | Encourages neural firing |
| Antagonist | Discourages neural firing |
| Reuptake inhibitor | Blocks neurotransmitter reabsorption into the sending cell |
| Drug category | Typical effect | CED examples |
|---|---|---|
| Stimulant | Increased neural activity | Caffeine, cocaine |
| Depressant | Decreased neural activity | Alcohol |
| Hallucinogen | Distorted perception and/or cognition | Marijuana |
| Opioid | Pain relief | Heroin |
Repeated psychoactive-drug use can produce tolerance and/or addiction. If addiction develops, stopping use can produce significant withdrawal symptoms. Do not assume a category label describes every effect of every dose; the CED statements describe typical effects.